Современные яды: Дозы, действие, последствия

Колок Алан





Carson, Rachel. Silent Spring. New York: Houghton Mifflin Company, 1961. На русском языке: Карсон, Р. Безмолвная весна. – М.: Прогресс, 1965.

Colborn, T., D. Dumanoski, and J. P. Myers. Our Stolen Future: Are We Threatening Our Fertility, Intelligence, and Survival? A Scientific Detective Story. New York: Penguin Books, 1997.

Emsley, J. The Elements of Murder. Oxford, UK: Oxford University Press, 2005.

Kean, S. The Disappearing Spoon: And Other True Tales of Madness, Love, and the History of the World from the Periodic Table of the Elements. New York: Hachette Book Group, 2010. На русском языке: Кин С. Исчезающая ложка, или Удивительные истории из жизни периодической таблицы Менделеева. – М.: Эксмо, 2015.

Klaassen, C. D. Toxicology: The Basic Science of Poisons. 8th ed. New York: McGraw-Hill, 2013.

Mukherjee, S. The Emperor of All Maladies. New York: Simon and Schuster, 2010.

Randall, D., W. Burggren, and K. French. Eckert Animal Physiology: Mechanisms and Adaptations. New York: W. H. Freeman, 2001.

Stelljes, M. E. Toxicology for Non-Toxicologists. Rockville, MD: ABS Group, 2000.

Weston, A., and C. C. Harris. "Chemical Carcinogenesis." In Cancer Medicine, 8th ed., edited by W. K. Hong, R. C. Bast Jr., W. N. Hait, D. W. Kufe, R. E. Pollock, R. R. Weichselbaum, J. F. Holland, and E. Frei III. Shelton, CT: People's Medical Publishing House, 2009.



Глава 1. Все зависит от дозы

Dorne, J. L., and A. G. Renwick. "The Refinement of Uncertainty / Safety Factors in Risk Assessment by the Incorporation of Data on Toxicokinetic Variability in Humans. Toxicological Sciences 86 (2005): 20–26.

Jager, T. "Bad Habits Die Hard: The NOEC's Persistence Reflects Poorly on Ecotoxicology." Environmental Toxicology and Chemistry 31 (2012): 228–29.

Landis, W. G., and Chapman, P. M. "Well Past Time to Stop Using NOELs and LOELs." Integrated Environmental Assessment and Management 7 (2011): vi – viii.

Глава 3. Человек как животное

Adkins, R. M., E. L. Gelke, D. Rowe, and R. L. Honeycutt. «Molecular Phylogeny and Divergence Time Estimates for Major Rodent Groups: Evidence for Multiple Genes.» Molecular Biology and Evolution 18 (2001): 777–91.

Andrews, P. L. R. "Laboratory Invertebrates: Only Spineless, or Spineless and Painless?" ILAR Journal 52 (2011): 121–25.

Berman, H. M., L. F. Ten Eyck, D. S. Goodsell, N. M. Haste, A. Kornev, and S. S. Taylor. "The cAMP Binding Domain: An Ancient Signaling Module." Proceedings of the National Academy of Sciences USA 102 (2005): 45–50.

Beyer, L. A., B. D. Beck, and T. A. Lewandowski. "Historical Perspective on the Use of Animal Bioassays to Predict Carcinogenicity: Evolution in Design and Recognition of Utility." Critical Reviews in Toxicology 41 (2011): 321–28.

Cohen, S. M., L. L. Arnold, M. Cano, M. Ito, E. M. Garland, and R. A. Shaw. "Calcium Phosphate-Containing Precipitate and the Carcinogenicity of Sodium Salts in Rats." Carcinogenesis 21 (2000): 783–92.

Gold, L. S., T. H. Slone, N. B. Manley, and L. Bernstein. "Target Organs in Chronic Bioassays of 533 Chemical Carcinogens." Environmental Health Perspectives 93 (1991): 233–46.

Gold, L. S., L. Bernstein, R. Magaw, and T. H. Slone. "Interspecies Extrapolation in Carcinogenesis: Prediction between Rats and Mice." Environmental Health Perspectives 81 (1989): 211–219.

Harvey-Clark, C. "IACUC Challenges in Invertebrate Research." ILAR Journal 52 (2011): 213–20.

Hurst, L. D., and N. G. Smith. "Do Essential Genes Evolve Slowly?" Current Biology 9 (1999): 747–50.

Jordan, I. K., I. B. Rogozin, Y. I. Wolf, and E. V. Koonin. "Essential Genes Are More Evolutionarily Conserved than Are Nonessential Genes in Bacteria." Genome Research 12 (2002): 962–68.

Kawakami, T., R. Ishimura, K. Nohara, K. Takeda, C. Tohyama, and S. Ohsako. "Differential Susceptibilities of Holtzman and Sprague-Dawley Rats to Fetal Death and Placental Dysfunction Induced by 2,3,7,8-teterachlorodibenzo-p-dioxin (TCDD) despite the Identical Primary Structure of the Aryl Hydrocarbon Receptor." Toxicology and Applied Pharmacology 212 (2006): 224–36.

Mather, J. A. "Philosophical Background of Attitudes toward the Treatment of Invertebrates." ILAR Journal 52 (2011): 205–12.

Putz, O., C. B. Schwartz, S. Kim, G. A. LeBlanc, R. L. Cooper, and G. S. Prins. "Neonatal Low– and High-Dose Exposure to Estradiol Benzoate in the Male Rat: I. Effects on the Prostate Gland." Biology of Reproduction 65 (2001): 1496–505.

Putz, O., C. B. Schwartz, G. A. LeBlanc, R. L. Cooper, and G. S. Prins. "Neonatal Low– and High-Dose Exposure to Estradiol Benzoate in the Male Rat: II. Effects on Male Puberty and the Reproductive Tract." Biology of Reproduction 65 (2001): 1506–17.

Rand-Weaver, M., L. Margiotta-Casaluci, A. Patel, G. H. Panter, S. F. Owen, and J. P. Sumpter. "The Read-Across Hypothesis and Environmental Risk Assessment of Pharmaceuticals." Environmental Science and Technology 47 (2013): 11 384–95.

Rinaldi, J., J. Wu, J. Yang, C. Y. Ralston, B. Sankaran, S. Moreno, and S. S. Taylor. "Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling." Structure 18 (2010): 1471–82.

Rothen, D., S. Baran, and M. Perret-Gentil. "Are Zebrafish the New Mice?" ALN magazine (2014).

Vargo-Gogola, T., and J. M. Rosen. "Modeling Breast Cancer: One Size Does Not Fit All." Nature Reviews Cancer 7 (2007): 659–72.

Глава 5. Защита организма

Abbott, N. J. «Blood – Brain Barrier Structure and Function and the Challenges for CNS Drug Delivery.» Journal of Inherited Metabolic Disease 36 (2013): 437–49.

Pardridge, W. M. "Drug Delivery to the Brain." Journal of Cerebral Blood Flow and Metabolism 17 (1997): 713–31.

Patel, M. M., B. R. Goyal, S. V. Bhadada, J. S. Bhatt, and A. F. Amin. "Getting into the Brain." CNS Drugs 23 (2009): 35–58.

Глава 7. Частицы-путешественницы

Blackwell, B. R., K. J. Wooten, M. D. Buser, B. J. Johnson, G. P. Cobb, and P. N. Smith. «Occurrence and Characterization of Steroid Growth Promoters Associated with Particulate Matter Originating from Beef Cattle Feedyards.» Environmental Science and Technology 49 (2015): 8796–803.

Hamra, G. B., N. Guha, A. Cohen, F. Laden, O. Raaschou-Nielsen, J. M. Samet, P. Vineis, et al. "Outdoor Particulate Matter Exposure and Lung Cancer: A Systematic Review and Meta-Analysis." Environmental Health Perspectives 122 (2014): 906–11. doi:10.1289 / ehp.1408092.

Jonker, M. T. O., and L. van Mourik. "Exceptionally Strong Sorption of Infochemicals to Activated Carbon Reduces Their Bioavailability to Fish." Environmental Toxicology and Chemistry 33 (2014): 493–99.

Liu, L., B. Urch, R. Poon, M. Szyszkowicz, M. Speck, D. R. Gold, A. J. Wheeler, et al. "Effects of Ambient Coarse, Fine, and Ultrafine Particles and Their Biological Constituents on Systemic Biomarkers: A Controlled Human Exposure Study." Environmental Health Perspectives 123 (2015): 534–40. doi:10.1289/ehp.1408387.

McEachran, A. D., B. R. Blackwell, J. D. Hanson, K. J. Wooten, G. D. Mayer, S. B. Cox, and P. N. Smith. "Antibiotics, Bacteria, and Antibiotic Resistance Genes: Aerial Transport from Cattle Feed Yards via Particulate Matter." Environmental Health Perspectives 123 (2015): 337–43. doi:10.1289/ehp.1408555.

Sandstrom, T., and B. Forsberg. "Desert Dust: An Unrecognized Source of Dangerous Air Pollution?" Epidemiology 19 (2008): 808–9.

Valavanidis, A., K. Fiotakis, and T. Vlachogianni. "Airborne Particulate Matter and Human Health: Toxicological Assessment and Importance of Size and Composition of Particles for Oxidative Carcinogenic Mechanisms." Journal of Environmental Science and Health Part C: Environmental Carcinogenesis Ecotoxicology Reviews 26 (2008): 339–62. doi:10.1080/10590500802494538.

Vignati, D. A., T. Dworak, B. Ferrari, B. Koukal, J. L. Loizeau, M. Minouflet, M. I. Camusso, S. Polesello, and J. Dominik. "Assessment of the Geochemical Role of Colloids and Their Impact on Contaminant Toxicity in Freshwaters: An Example from the Lambro-Po System (Italy)." Environmental Science and Technology 39 (2005): 489–97.

Von Essen, S. G., and B. W. Auvermann. "Health Effects from Breathing Air Near CAFOs for Feeder Cattle or Hogs." Journal of Agromedicine 10 (2005): 55–64.

Глава 8. Природные яды: растительные и животные токсины

Fry, B. G. «From Genome to 'Venome': Molecular Origin and Evolution of the Snake Venom Proteome Inferred from Phylogenetic Analysis of Toxin Sequences and Related Body Proteins.» Genome Research 15 (2005): 403–20.

Глава 9. Металлы: дар и проклятие

Clarkson, T. W. «The Three Modern Faces of Mercury.» Environmental Health Perspectives 110 (2002): 11–23.

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Hakim, J. "The Story of the Atom." American Federation of Teachers (2002): 12–25.

Le, T. T., W. J. Peijnenburg, A. J. Hendriks, and M. G. Vijver. "Predicting Effects of Cations on Copper Toxicity to Lettuce (Lactuca sativa) by the Biotic Ligand Model." Environmental Toxicology and Chemistry 31 (2012): 355–59.

Lessler, M. A. "Lead and Lead Poisoning from Antiquity to Modern Times." Ohio Journal of Science 88 (1988): 78–84.

Nicole, W. "Evolutionary Selection for Arsenic Resistance: The Case of the Atacamenos of the Andes Highlands." Environmental Health Perspectives 121 (2013): A31.

Niyogi, S., and C. H. Wood. "Biotic Ligand Model, a Flexible Tool for Developing Site-Specific Water Quality Guidelines for Metals." Environmental Science and Technology 38 (2004): 6177–92.

Paquin, P. R., J. W. Gorsuch, S. Apte, G. E. Batley, K. C. Bowles, P. G. C. Campbell, C. G. Delos, et al. "The Biotic Ligand Model: A Historical Overview." Comparative Biochemistry and Physiology Part C 133 (2002): 3–35.

Przygoda, G., J. Feldmann, and W. Cullen. "The Arsenic Eaters of Styria: A Different Picture of People Who Were Chronically Exposed to Arsenic." Applied Organometallic Chemistry 15 (2001): 457–62.

Глава 10. Горение

Ashby, J., and D. Paton. «The Influence of Chemical Structure on the Extent and Sites of Carcinogenesis for 522 Rodent Carcinogens and 55 Different Human Carcinogen Exposures.» Mutation Research 286 (1993): 3–74.

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DeVita, V. T. Jr., and E. Chu. "A History of Cancer Chemotherapy." Cancer Research 68 (2008): 8643–53.

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Глава 11. Лекарства, наркотики и токсикология зависимости

Blum, K., J. G. Cull, E. R. Braverman, and D. E. Comings. «Reward Deficiency Syndrome.» American Scientist 84 (1996): 132–45.

Blum, K., A. L. C. Chen, J. Giordano, J. Borsten, T. J. H. Chen, M. Hauser, T. Simpatico, J. Femino, E. R. Braverman, and D. Barh. "The Addictive Brain: All Roads Lead to Dopamine." Journal of Psychoactive Drugs 44 (2012): 134–43.

De Pasquale, A. "Pharmacognosy: The Oldest Modern Science." Journal of Ethnopharmacology 11 (1984): 1–16.

Glander, K. E. "Nonhuman Primate Self-Medication with Wild Plants." Chap. 12 in Eating on the Wild Side: The Pharmacologic, Ecologic, and Social Implications of Using Noncultigens. Tucson, AZ: University of Arizona Press, 1994.

Hardy, K., S. Buckley, M. J. Collins, A. Estalrrich, D. Brothwell, L. Copeland, A. Garcнa-Tabernero, et al. "Neanderthal Medics? Evidence for Food, Cooking, and Medicinal Plants Entrapped in Dental Calculus." Naturwissenschaften 99 (2012): 617–26. doi:10.1007 / s00114-012-0942-0. Epub 2012 Jul 18.

Huffman, M. A. "Current Evidence for Self-Medication in Primates: A Multidisciplinary Perspective." Yearbook of the Journal of Physical Anthropology 40 (1997): 171–200.

Jones, A. W. "Early Drug Discovery and the Rise of Pharmaceutical Chemistry." Drug Testing and Analysis 3 (2011): 337–44.

Nichols, D. E. "Hallucinogens." Pharmacology and Therapeutics 101 (2004): 131–81.

Quaglio, G., A. Fornasiero, P. Mezzelani, S. Morechini, F. Lugoboni, and A. Lechi. "Anabolic Steroids: Dependence and Complications of Chronic Use." Internal and Emergency Medicine 4 (2009): 289–96.

Sullivan, R. J., and E. H. Hagen. "Psychotropic Substance-Seeking: Evolutionary Pathology or Adaptation?" Addiction 97 (2002): 389–400.

Tan, R. S., and M. C. Scally. "Anabolic Steroid-Induced Hypogonadism: Towards a Unified Hypothesis of Anabolic Steroid Action." Medical Hypotheses 72 (2009): 723–28.

Westermeyer, J. "The Pursuit of Intoxication: Our 100-Century-Old Romance with Psychoactive Substances." American Journal of Drug and Alcohol Abuse 14 (1988): 175–87.

Wood, R. I. "Reinforcing Aspects of Androgens." Physiology and Behavior 83 (2004): 279–89.

Глава 12. 70 000 лет пестицидов

Bouwman, H., H. van den Berg, and H. Kylin. «DDT and Malaria Prevention: Addressing the Paradox.» Environmental Health Perspectives 119 (2011): 744–47.

Dunlap, T. R. "Science as a Guide in Regulating Technology: The Case of DDT in the United States." Social Studies of Science 8 (1978): 265–85.

McWilliams, J. E. "'The Horizon Opened Up Very Greatly': Leland O. Howard and the Transition to Chemical Insecticides in the United States, 1894–1927." Agricultural History 82 (2008): 468–95.

O'Shaughnessy, P. T. (2008) "Parachuting Cats and Crushed Eggs: The Controversy over the Use of DDT to Control Malaria." American Journal of Public Health 98: 1940–48.

Smith, A. E., and D. M. Secoy. "Forerunners of Pesticides in Classical Greece and Rome." Journal of Agricultural and Food Chemistry 23 (1975): 1050–55.

Глава 13. История регуляторных мер

Botting, J. «The History of Thalidomide.» Drug News & Perspectives 15 (2002): 604–11.

Gaughan, A. "Harvey Wiley, Theodore Roosevelt, and the Federal Regulation of Food and Drugs." Студенческая работа, Harvard Law School, 2004.

Herbst, A. L., D. C. Poskanzer, S. J. Robboy, L. Friedlander, and R. E. Scully. "Prenatal Exposure to Stilbestrol: A Prospective Comparison of Exposed Female Offspring with Unexposed Controls." New England Journal of Medicine 292 (1975): 334–39.

Herbst, A. L., H. Ulfelder, and D. C. Poskanzer. "Adenocarcinoma of the Vagina." New England Journal of Medicine 284 (1971): 878–81.

Janssen, W. F. "The Story of the Laws behind the Labels." FDA Consumer. US Food and Drug Administration, 1981.

Klimko, K. "FDA's Contradictory Decisions Related to the Delaney Clause." Студенческая работа, Harvard Law School, 2011.

Neltner, T. G., N. R. Kulkarni, H. M. Alger, M. V. Maffini, E. D. Bongard, N. D. Fortin, and E. D. Olson. "Navigating the U. S. Food Additive Regulatory Program." Comprehensive Reviews in Food Science and Food Safety 10 (2011): 342–68.

Nicole, W. "Secret Ingredients: Who Knows What's in Your Food?" Environmental Health Perspectives 121 (2013): A126–33.

Quinn, R. "Rethinking Antibiotic Research and Development: World War II and the Penicillin Collaborative." American Journal of Public Health 103 (2013): 426–34.

US Food and Drug Administration. "Guidance for Industry: Frequently Asked Questions about GRAS." US Department of Health and Human Services, 2004.

Wax, P. M. "Elixirs, Diluents, and the Passage of the 1938 Federal Food, Drug, and Cosmetic Act." Annals of Internal Medicine 122 (1995): 456–61.

Глава 14. Низкодозированные химические канцерогены

Asch, P. «Food Safety Regulation: Is the Delaney Clause the Problem or Symptom?» Policy Sciences 23 (1990): 97–110.

Baker, M. "Insights from the Structure of Estrogen Receptor into the Evolution of Estrogens: Implications for Endocrine Disruption." Biochemical Pharmacology 82 (2011): 1–8.

Blair, R. M., H. Fang, W. S. Branham, B. S. Hass, S. L. Dial, C. L. Moland, W. Tong, L. Shi, R. Perkins, and D. M. Sheehan. "The Estrogen Receptor Binding Affinities of 188 Natural and Xenochemicals: Structural Diversity of Ligands." Toxicological Sciences 54 (2000): 138–53.

Creton, S., M. J. Aardema, P. L. Carmichael, J. S. Harvey, F. L. Martin, R. F. Newbold, M. R. O'Donovan, et al. "Cell Transformation Assays for Prediction of Carcinogenic Potential: State of the Science and Future Research Needs." Mutagenesis 27, no. 1 (Jan 2012): 93–101. doi:10.1093/mutage/ger053.

Fagan, D. "The Learning Curve." Nature 490 (25 October 2012): 462–65.

Junod, S. W. "Sugar: A Cautionary Tale." US Food and Drug Administration, 2003. по состоянию на 1 января 2016.

Levenson, A. S., and V. C. Jordan. "The First Hormone-Responsive Breast Cancer Cell Line." Cancer Research 57 (1997): 3071–78.

Melnick, R., G. Lucier, M. Wolfe, R. Hall, G. Stancel, G. Prins, M. Gallo, et al. "Summary of the National Toxicology Program's Report of the Endocrine Disruptors Low-Dose Peer Review." Environmental Health Perspectives 110 (2002): 427–31.

Vandenberg, L. N., T. Colborn, T. B. Hayes, J. J. Heindel, D. R. Jacobs Jr., D.-H. Lee, T. Shioda, et al. "Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses." Endocrine Reviews 33 (2012): 1–78.

Welshons, W. V., K. A. Thayer, B. M. Judy, J. A. Taylor, E. M. Curran, and F. S. vom Saal. "Large Effects from Small Exposures: I. Mechanisms for Endocrine-Disrupting Chemicals with Estrogenic Activity." Environmental Health Perspectives 111 (2003): 994–1006.

Yager, J. D., and N. E. Davidson. "Estrogen Carcinogenesis in Breast Cancer." New England Journal of Medicine 354 (2006): 270–82.

Глава 15. СОЗ и «Безмолвная весна»

Adeola, F. O. «Boon or Bane? The Environmental and Health Impacts of Persistent Organic Pollutants (POPs).» Human Ecology Review 11 (2004): 27–35.

American Chemical Society. "Rachel Carson's Silent Spring: National Historic Chemical Landmarks." American Chemical Society, 2013.

Ballschmiter, K., R. Hackenberg, W. M. Jarman, and R. Looser. "Man-Made Chemicals Found in Remote Areas of the World: The Experimental Definition for POPs." Environmental Science & Pollution Research 9 (2002): 274–88.

Bard, S. M. "Global Transport of Anthropogenic Contaminants and the Consequences for the Arctic Marine Ecosystem." Marine Pollution Bulletin 38 (1999): 359–79.

Bonefeld-Jorgensen, E. C. "Biomonitoring in Greenland: Human Biomarkers of Exposure and Effects – A Short Review." Rural and Remote Health 10 (2010): 1362.

Bowerman, W. W., D. A. Best, T. G. Grubb, G. M. Zimmerman, and J. P. Giesy. "Trends of Contaminants and Effects in Bald Eagles of the Great Lakes Basin." Environmental Monitoring and Assessment 53 (1998): 197–212.

Donaldson, S. G., J. Van Oostdam, C. Tikhonov, M. Feeley, B. Armstrong, P. Ayotte, O. Boucher, et al. "Environmental Contaminants and Human Health in the Canadian Arctic." Science of the Total Environment 408 (2010): 5165–234. doi:10.1016/j.scitotenv.2010.04.059. Epub 2010 Aug 21.

Глава 16. Токсичные средства гигиены

Boxall, A. B., M. A. Rudd, B. W. Brooks, D. J. Caldwell, K. Choi, S. Hickmann, E. Innes, et al. «Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?» Environmental Health Perspectives 120 (2012): 1221–29. doi:10.1289 / ehp.1104477. Epub 2012 May 30.

Brausch, J. M., and G. M. Rand. "A Review of Personal Care Products in the Aquatic Environment: Environmental Concentrations and Toxicity." Chemosphere 82 (2011): 1518–32.

Brooks, B. W. "Fish on Prozac (and Zoloft): Ten Years Later." Aquatic Toxicology 151 (2014): 61–67.

Brooks, B. W., C. K. Chambliss, J. K. Stanley, A. Ramirez, K. E. Banks, R. D. Johnson, and R. J. Lewis. "Determination of Select Antidepressants in Fish from an Effluent-Dominated Stream." Environmental Toxicology and Chemistry 24 (2005): 464–69.

Brooks, B. W., C. M. Foran, S. M. Richards, J. Weston, P. K. Turner, J. K. Stanley, K. R. Solomon, M. Slattery, and T. W. La Point. "Aquatic Ecotoxicology of Fluoxetine." Toxicology Letters 142 (2003): 169–83.

Brooks, B. W., P. K. Turner, J. K. Stanley, J. J. Weston, E. A. Glidewell, C. M. Foran, M. Slattery, T. W. La Point, and D. B. Huggett. "Waterborne and Sediment Toxicity of Fluoxetine to Select Organisms." Chemosphere 52 (2003): 135–42.

Fabbri, E. "Pharmaceuticals in the Environment: Expected and Unexpected Effects on Aquatic Fauna." Annals of the New York Academy of Sciences 1340 (2015): 20–28.

Gonzalez-Rey, M., N. Tapie, K. Le Menach, M.-H. Devier, H. Budzinski, and M. J. Bebianno. "Occurrence of Pharmaceutical Compounds and Pesticides in Aquatic Systems." Marine Pollution Bulletin 96 (2015): 384–400.

James-Todd, T., M. B. Terry, J. Rich-Edwards, A. Deierlein, and R. Senie. "Childhood Hair Product Use and Earlier Age at Menarche in a Racially Diverse Study Population: A Pilot Study." Annals of Epidemiology 21 (2011): 461–65. doi:10.1016 / j.annepidem.2011.01.009. Epub 2011 Mar 21.

Kessler, R. "More than Cosmetic Changes: Taking Stock of Personal Care Product Safety." Environmental Health Perspectives 123 (2015): A120–27. doi:10.1289 / ehp.123-A120.

Larsson, J. D. G., C. de Pedro, and N. Paxeus. "Effluent from Drug Manufactures Contain Extremely High Levels of Pharmaceuticals." Journal of Hazardous Materials 148 (2007): 751–55. Epub 2007 Jul 6.

Larsson, J. D. G. "Pollution from Drug Manufacturing: Review and Perspectives." Philosophical Transactions of the Royal Society B 369 (2014). doi:10.1098 / rstb.2013.0571.

Lubick, N. "India's Drug Problem." Nature 457 (2009): 640–41. doi:10.1038 / 457640a.

Matthiessen, P., and L. Weltje. "A Review of the Effects of Azole Compounds in Fish and Their Possible Involvement in Masculinization of Wild Fish Populations." Critical Reviews in Toxicology 45 (2015): 453–67. doi:10.3109 / 10408444.2015.1018409. Epub 2015 Apr 21.

Myers, S. L., C. Z. Yang, G. D. Bittner, K. L. Witt, R. R. Tice, and D. D. Baird. "Estrogenic and Anti-Estrogenic Activity of Off-the-Shelf Hair and Skin Care Products." Journal of Exposure Science and Environmental Epidemiology 25 (2015): 271–77. doi:10.1038 / jes.2014.32. Epub 2014 May 21.

Oaks, J. L., M. Gilbert, M. Z. Virani, R. T. Watson, C. U. Meteyer, B. A. Rideout, H. L. Shivaprasad, et al. "Diclofenac Residues as the Cause of Vulture Population Decline in Pakistan." Nature 427 (12 February 2004): 630–33.

Overturf, M. D., J. C. Anderson, Z. Pandelides, L. Beyger, and D. A. Holdway. "Pharmaceuticals and Personal Care Products: A Critical Review of the Impacts on Fish Reproduction." Critical Reviews in Toxicology 45 (2015): 469–91. doi:10.3109 / 10408444.2015.1038499. Epub 2015 May 6.

Sumpter, J. P., R. L. Donnachie, and A. C. Johnson. "The Apparently Very Variable Potency of the Anti-Depressant Fluoxetine." Aquatic Toxicology 151 (2014): 57–60.

Ternes, T. A., A. Joss, and H. Siegrist. "Scrutinizing Pharmaceuticals and Personal Care Products in Wastewater Treatment." Environmental Science & Technology 38 (2004): 392A – 399A.

Tiwary, C. M. "Premature Sexual Development in Children Following the Use of Estrogen– or Placenta-Containing Hair Products." Clinical Pediatrics 37 (1998): 733–39.

Wise, L. A., J. R. Palmer, D. Reich, Y. C. Cozier, and L. Rosenberg. "Hair Relaxer Use and Risk of Uterine Leiomyomata in African-American Women." American Journal of Epidemiology 175 (2012): 432–40. doi:10.1093 / aje / kwr351.

Глава 17. Определение пола: химические вещества и репродукция

Barber, L. B., A. M. Vajda, C. Douville, D. O. Norris, and J. H. Writer. «Fish Endocrine Disruption Responses to a Major Wastewater Treatment Facility Upgrade.» Environmental Science & Technology 46 (2012): 2121–31.

Buck Louis, G. M., M. A. Clooney, and C. M. Peterson. "The Ovarian Dysgenesis Syndrome." Journal of Developmental Origins of Health and Disease 2 (2011): 25–35.

Devlin, R. H., and Y. Nagahama. "Sex Determination and Sex Differentiation in Fish: An Overview of Genetic, Physiological, and Environmental Influences." Aquaculture 208 (2002): 191–364.

Georges, A., T. Ezaz, A. E. Quinn, and S. D. Sarre. "Are Reptiles Predisposed to Temperature-Dependent Sex Determination?" Sexual Development 4 (2010): 7–15.

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Harris, C. A., P. B. Hamilton, T. J. Runnalis, V. Vinciotti, A. Henshaw, D. Hodgson, T. S. Coe, S. Jobling, C. R. Tyler, and J. P. Sumpter. "The Consequences of Feminization in Breeding Groups of Wild Fish." Environmental Health Perspectives 119 (2011): 306–11.

Hayes, T. B., V. Khoury, A. Narayan, M. Nazir, A. Park, T. Brown, L. Adame, et al. "Atrazine Induces Complete Feminization and Chemical Castration in Male African Clawed Frogs (Xenopus laevis)." Proceedings of the National Academy of Sciences USA 107 (2010): 4612–17.

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Kidd, K., P. J. Blanchfield, K. H. Mills, V. P. Palace, R. E. Evans, J. M. Lazorchak, and R. W. Flick. "Collapse of a Fish Population after Exposure to a Synthetic Estrogen." Proceedings of the National Academy of Sciences USA 104 (2007): 8897–901.

LeBlanc, G. A. "Are Environmental Sentinels Signaling?" Environmental Health Perspectives 103 (1995): 888–90.

MacLachlan, N. J. "Ovarian Disorders in Domestic Animals." Environmental Health Perspectives 73 (1987): 27–33.

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Nakamura, M. "Morphological and Physiological Studies on Gonadal Sex Differentiation in Teleost Fish." Aqua-BioScience Monographs 6 (2013): 1–47.

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Smith, C. A., K. N. Roeszler, T. Ohnesorg, D. M. Cummins, P. G. Farlie, T. J. Doran, and A. H. Sinclair. "The Avian Z-Linked Gene DMRT1 Is Required for Male Sex Determination in the Chicken." Nature 461 (10 September 2009): 267–71.

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Vaiman, D., and E. Pailhoux. "Mammalian Sex Reversal and Intersexuality: Deciphering the Sex-Determination Cascade." Trends in Genetics 16 (2000): 488–94.

Zheng, Z., and M. J. Cohn. "Developmental Basis of Sexually Dimorphic Digit Ratios." Proceedings of the National Academy of Sciences USA 108 (2011): 16289–94.

Глава 18. Воздействие на самой ранней стадии: трансгенерационная токсикология

Anway, M. D., A. S. Cupp, M. Uzumcu, and M. K. Skinner. «Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility.» Science 308 (2005): 1466–69.

Anway, M. D., C. Leathers, and M. K. Skinner. "Endocrine Disruptor Vinclozolin-Induced Epigenetic Transgenerational Adult-Onset Disease." Endocrinology 147 (2006): 5515–23. Epub 2006 Sep 14.

Bannister, A. J., and T. Kouzarides. "Regulation of Chromatin by Histone Modifications." Cell Research 21 (2011): 381–95.

Barker, D. K. P., C. Osmond, P. D. Winter, B. Margetts, and S. J. Simmonds. "Weight in Infancy and Death from Ischaemic Heart Disease." Lancet 334 (9 September 1989): 577–80.

Carey, N. "Beyond DNA: Epigenetics." In The Epigenetic Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance. New York: Columbia University Press, 2012. Excerpted in Natural History Online (n.d.).

Esteller, M. "Non-Coding RNAs in Human Disease." Nature Reviews Genetics 12 (2011): 861–74.

Heijmans, B. T., E. W. Tobi, A. D. Stein, H. Putter, G. J. Blauw, E. S. Susser, P. E. Slagboom, and L. H. Lumey. "Persistent Epigenetic Differences Associated with Prenatal Exposure to Famine in Humans." Proceedings of the National Academy of Sciences USA 105 (2008): 17046–9. doi:10.1073 / pnas.0806560105. Epub 2008 Oct 27.

Jirtle, R. L., and M. K. Skinner. "Environmental Epigenomics and Disease Susceptibility." Nature Reviews Genetics 8 (2007): 253–62.

Louis, G. M., M. A. Cooney, and C. M. Peterson. "The Ovarian Dysgenesis Syndrome." Journal of Developmental Origins of Health and Disease 2 (2011): 25–35.

Lumey, L. H., M. B. Terry, L. Delgado-Cruzata, Y. Liao, Q. Wang, E. Susser, I. McKeague, and R. M. Santella. "Adult Global DNA Methylation in Relation to Pre-Natal Nutrition." International Journal of Epidemiology 41 (2012): 116–23. doi:10.1093 / ije / dyr137. Epub 2011 Sep 29.

Martin, G. M. "Epigenetic Drift in Aging Identical Twins." Proceedings of the National Academy of Sciences USA 102 (2005): 10413–14.

Nilsson, E. E., and M. K. Skinner. "Environmentally Induced Epigenetic Transgenerational Inheritance of Disease Susceptibility." Translational Research 165 (2015): 12–17.

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Poulsen, P., M. Esteller, A. Vaag, and M. F. Fraga. "The Epigenetic Basis of Twin Discordance in Age-Related Diseases." Pediatric Research 61 (2007): 38R – 42R.

Prins, G. S. "Estrogen Imprinting: When Your Epigenetic Memories Come Back to Haunt You." Endocrinology 149 (2008): 5919–21.

Reik, W., W. Dean, and J. Walter. "Epigenetic Reprogramming in Mammalian Development." Science 293 (10 August 2001): 1089–92.

Reik, W., and J. Walter. "Genomic Imprinting: Parental Influence on the Genome." Nature Reviews Genetics 2 (2001): 21–32.

Schmidt, C. W. "Uncertain Inheritance Transgenerational Effects of Environmental Exposures." Environmental Health Perspectives 121 (2013): A298 – A303.

Uzumcu, M., A. M. Zama, and E. Oruc. "Epigenetic Mechanisms in the Actions of Endocrine-Disrupting Chemicals: Gonadal Effects and Role in Female Reproduction." Reproduction in Domestic Animals 47 (2012):338–47. doi:10.1111 / j.1439–0531.2012.02096.x.

Xin, F., M. Susiarjo, and M. S. Bartolomei. "Multigenerational and Transgenerational Effects of Endocrine Disrupting Chemicals: A Role for Altered Epigenetic Regulation?" Seminars in Cell Developmental Biology 43 (2015): 66–75. doi:10.1016 / j.semcdb.2015.05.008 [Epub ahead of print].

Zhang, X., and S. M. Ho. "Epigenetics Meets Endocrinology." Journal of Molecular Endocrinology 46 (2011): R11 – R32.

Глава 19. Еще раз о природных ядах

Aquzzi, A., and J. Falsig, eds. «Prion Propagation, Toxicity, and Degradation.» Nature Neuroscience 15 (2012): 936–39.

Espelund, M., and D. Klaveness. "Botulism Outbreaks in Natural Environments – An Update." Frontiers in Microbiology 5 (11 June 2014): 287. doi:10.3389 / fmicb.2014.00287.

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Saunders, S. E., S. L. Bartelt-Hunt, and J. C. Bartz. "Prions in the Environment: Occurrence, Fate, and Mitigation." Prion 2 (2008): 162–69. Epub 2008 Oct 26.

Saunders, S. E., J. C. Bartz, and S. L. Bartelt-Hunt. "Soil-Mediated Prion Transmission: Is Local Soil-Type a Key Determinant of Prion Disease Incidence?" Chemosphere 87 (2012): 661–67.

Texas Department of Insurance. "Poison Ivy, Oak, and Sumac Factsheet." HS04-064B (3-07). Texas Department of Insurance, Division of Workers' Compensation (TDI / DWC) [n.d.].

Глава 20. Устойчивость к химикатам

Arias, C. A., and B. E. Murray. «Antibiotic-Resistant Bugs in the 21st Century – A Clinical Super-Challenge.» New England Journal of Medicine 360 (2009): 439–43. doi:10.1056 / NEJMp0804651.

Bass, C., and L. M. Field. "Gene Amplification and Insecticide Resistance." Pest Management Science 67 (2011): 886–90.

Bouki, C., D. Venieri, and E. Diamadopoulos. "Detection and Fate of Antibiotic Resistant Bacteria in Wastewater Treatment Plants: A Review." Ecotoxicology and Environmental Safety 91 (2013): 1–9. doi:10.1016 / j.ecoenv.2013.01.016. Epub 2013 Feb 13.

Brown, M. G., and D. L. Balkwill. "Antibiotic Resistance in Bacteria Isolated from the Deep Terrestrial Subsurface." Microbial Ecology 57 (2009): 484–93.

Davies, J., and D. Davies. "Origins and Evolution of Antibiotic Resistance." Microbiology and Molecular Biology Reviews 74 (2010): 417–33. doi:10.1128 / MMBR.00016–10.

Ffrench-Constant, R. H. "The Molecular Genetics of Insecticide Resistance." Genetics 194 (2013): 807–15. doi:10.1534 / genetics.112.141895.

Gonzalez-Rey, M., N. Tapie, K. Le Menach, M. H. Dйvier, H. Budzinski, and M. J. Bebianno. "Occurrence of Pharmaceutical Compounds and Pesticides in Aquatic Systems." Marine Pollution Bulletin 96 (2015): 384–400. doi:10.1016 / j.marpolbul.2015.04.029. Epub 2015 May 18.

Hartley, C. J., R. D. Newcomb, R. J. Russell, C. G. Yong, J. R. Stevens, D. K. Yeates, J. La Salle, and J. G. Oakeshott. "Amplification of DNA from Preserved Specimens Shows Blowflies Were Preadapted for the Rapid Evolution of Insecticide Resistance." Proceedings of the National Academy of Sciences 103 (2006): 8757–62.

Heuer, H., and K. Smalla. "Horizontal Gene Transfer between Bacteria." Environmental Biosafety Research 6 (2007): 3–13. Epub 2007 Oct 26.

Kim, S., and D. S. Aga. "Potential Ecological and Human Health Impacts of Antibiotics and Antibiotic-Resistant Bacteria from Wastewater Treatment Plants." Journal of Toxicology and Environmental Health, Part B Critical Reviews 10 (2007): 559–73.

Levine, D. P. "Vancomycin: A History." Clinical Infectious Diseases 42 (Supplement 1) (2006): S5 – S12. doi:10.1086 / 491709.

Levy, S. B., and B. Marshall. "Antibacterial Resistance Worldwide: Causes, Challenges, and Responses." Nature Medicine 10 (2004): S122–29.

Li, X., M. A. Schuler, and M. R. Berenbaum. "Molecular Mechanisms of Metabolic Resistance to Synthetic and Natural Xenobiotics." Annual Review of Entomology 52 (2007): 231–53. doi:10.1146 / annurev.ento.51.110104.151104.

Martinez, J. L. "Environmental Pollution by Antibiotics and by Antibiotic Resistance Determinants." Environmental Pollution 157 (2009): 2893–902. doi:10.1016 / j.envpol.2009.05.051. Epub 2009 Jun 27.

Mell, J. C., and R. J. Redfield. "Natural Competence and the Evolution of DNA Uptake Specificity." Journal of Bacteriology 196 (2014): 1471–83.

Meyers, J. I., M. Gray, and B. D. Foy. "Mosquitocidal Properties of IgG Targeting the Glutamate-Gated Chloride Channel in Three Mosquito Disease Vectors (Diptera: Culicidae). Journal of Experimental Biology 218 (2015): 1487–95.

Nielsen, K. M., P. J. Johnsen, D. Bensasson, and D. Daffonchio. "Release and Persistence of Extracellular DNA in the Environment." Environmental Biosafety Research 6 (2007): 37–53. Epub 2007 Sep 12.

Olofsson, S. K., P. Geli, D. I. Andersson, and O. Cars. "Pharmacodynamic Model to Describe the Concentration-Dependent Selection of Cefotaxime-Resistant Escherichia coli." Antimicrobial Agents and Chemotherapy 49 (2005): 5081–91.

Palecchi, L., A. Bartolini, F. Paradisi, and G. M. Rosolini. "Antibiotic Resistance in the Absence of Antimicrobial Use: Mechanisms and Implications." Expert Review of Anti-Infective Therapy 6 (2008): 725–32. doi:10.1586 / 14787210.6.5.725.

Palumbi, S. R. "Humans as the World's Greatest Evolutionary Force." Science 293 (2001): 1786–90.

Quinn, R. "Rethinking Antibiotic Research and Development: World War II and the Penicillin Collaborative." American Journal of Public Health 103 (2013): 426–34. doi:10.2105 / AJPH.2012.300693. Epub 2012 Jun 14.

Roberts, J. A., P. Kruger, D. L. Paterson, and J. Lipman. "Antibiotic Resistance – What's Dosing Got to Do with It?" Critical Care Medicine 36 (2008): 2433–40. doi:10.1097 / CCM.0b013e318180fe62.

Sexton, S. E., Z. Lei, and D. Zilberman. "The Economics of Pesticides and Pest Control." International Review of Environmental and Resource Economics 1 (2007): 271–326.

Tilman, D., J. Fargione, B. Wolff, C. D'Antonio, A. Dobson, R. Howarth, D. Schindler, W. H. Schlesinger, D. Simberloff, and D. Swackhamer. "Forecasting Agriculturally Driven Global Environmental Change." Science 292 (2001): 281–84.

Turnidge, J., and D. L. Paterson. "Setting and Revising Antibacterial Susceptibility Breakpoints." Clinical Microbiology Reviews 20 (2007): 391–408.

Verraes, C., S. Van Boxstael, E. Van Meervenne, E. Van Coillie, P. Butaye, B. Catry, M. A. de Schaetzen, et al. "Antimicrobial Resistance in the Food Chain: A Review." International Journal of Environmental Research and Public Health 10 (2013): 2643–69.

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Zhang, Y., C. Zhang, D. B. Parker, D. D. Snow, Z. Zhou, and X. Li. "Occurrence of Antimicrobials and Antimicrobial Resistance Genes in Beef Cattle Storage Ponds and Swine Treatment Lagoons." Science of the Total Environment 463–64 (2013): 631–38. doi:10.1016 / j.scitotenv.2013.06.016. Epub 2013 Jul 7.